ASSOCIATION BETWEEN MENARCHE AGE AND MENOPAUSAL SYMPTOMS

Authors

  • Muharam R Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia. http://orcid.org/0000-0001-5712-3931
  • Muhammad Ikhsan Indonesian Reproductive Medicine Research and Training Center, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  • Herdinda Erudite Rizkinya Indonesian Reproductive Medicine Research and Training Center, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i6.17706

Keywords:

menopause, symptoms, menarche age, Menopause Rating Scale

Abstract

Objective: The objective of this study was to assess the association between menarche age and menopausal symptoms.

Methods: A cross-sectional study with 100 perimenopause subjects. Every subject was assessed of their menopausal symptoms with validated menopause rating scale (MRS) questionnaire. Menopause symptoms were classified into somato-vegetative, psychological, and urogenital symptoms. Statistical analysis was used to assess menarche age and menopause symptoms associations.

Results: Out of 100 subjects, somato-vegetative, psychological, and urogenital symptoms were found in 46%, 68%, and 74% cases, respectively. Menarche age was varied between 10 and 17-year-old. There was a significant correlation between menarche age and psychological symptoms (p=0.034). However, there was no significant correlation between menarche age and somato-vegetative as well as urogenital symptoms (p=0.257; p=0.093).

Conclusion: There was a significant association between menarche age and psychological symptoms in perimenopause women. However, there was no association between menarche age and somato-vegetative as well as urogenital symptoms in perimenopause women.

Downloads

Download data is not yet available.

References

Obermeyer CM. Menopause across cultures: A review of the evidence. Menopause 2000;7(3):184-92.

World Health Organization. Research on the Menopause in the 1990s: Report of a WHO Scientific Group; 1996.

Morabia A, Costanza MC. International variability in ages at menarche, first livebirth, and menopause. World Health Organization collaborative study of neoplasia and steroid contraceptives. Am J Epidemiol 1998;148:1195-205.

Gold EB, Bromberger J, Crawford S, Samuels S, Greendale GA, Harlow SD, et al. Factors associated with age at natural menopause in a multiethnic sample of midlife women. Am J Epidemiol 2001;153(9):865-74.

Rymer J, Morris EP. Extracts from Clinical evidenceâ€: Menopausal symptoms. BMJ 2000;321(7275):1516-9.

Budakoglu II, Ozcan C, Eroglu D, Yanik F. Quality of life and postmenopausal symptoms among women in a rural district of the capital city of Turkey. Gynecol Endocrinol 2007;23(7):404-9.

Chedraui P, Aguirre W, Hidalgo L, Fayad L. Assessing menopausal symptoms among healthy middle aged women with the menopause rating scale. Maturitas 2007;57(3):271-8.

Waidyasekera H, Wijewardena K, Lindmark G, Naessen T. Menopausal symptoms and quality of life during the menopausal transition in Sri Lankan women. Menopause 2009;16(1):164-70.

Chedraui P, Hidalgo L, Chavez D, Morocho N, Alvarado M, Huc A. Menopausal symptoms and associated risk factors among postmenopausal women screened for the metabolic syndrome. Arch Gynecol Obstet 2007;275(3):161-8.

Jung SJ, Shin A, Kang D. Hormone-related factors and post-menopausal onset depression: Results from KNHANES (2010-2012). J Affect Disord 2015;175:176-83.

Heinemann LA, Potthoff P, Schneider HP. International versions of the Menopause Rating Scale (MRS). Health Qual Life Outcomes 2003;1:28.

Thenmozhi S. A study on psychological impact of menopause in Indian working women. Indian J Health Wellbeing 2014;5(12):1499.

Jung SJ, Shin A, Kang D. Menarche age, menopause age and other reproductive factors in association with post-menopausal onset depression: Results from Health Examinees Study (HEXA). J Affect Disord 2015;187:127-35.

Bisaga K, Petkova E, Cheng J, Davies M, Feldman JF, Whitaker AH. Menstrual functioning and psychopathology in a county-wide population of high school girls. J Am Acad Child Adolesc Psychiatry 2002;41(10):1197-204.

Herva A, Jokelainen J, Pouta A, Veijola J, Timonen M, Karvonen JT, et al. Age at menarche and depression at the age of 31 years: Findings from the Northern Finland 1966 Birth Cohort Study. J Psychosom Res 2004;57(4):359-62.

Sisk CL, Zehr JL. Pubertal hormones organize the adolescent brain and behavior. Front Neuroendocrinol 2005;26(3):163-74.

McEwen BS. Invited review: Estrogens effects on the brain: Multiple sites and molecular mechanisms. J Appl Physiol 2001;91(6):2785-801.

Divya MP, Rabbani SI, Mrudula G. Depression in pregnancy-consequences and treatment modalities. Int J Pharm Pharm Sci 2016;8(3):24-7.

Alomar MJ. Factors affecting postpartum depression among women of the UAE and Oman. Int J Pharm Pharm Sci 2015;7(7):231-3.

Published

01-06-2017

How to Cite

R, Muharam, et al. “ASSOCIATION BETWEEN MENARCHE AGE AND MENOPAUSAL SYMPTOMS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 6, June 2017, pp. 168-70, doi:10.22159/ajpcr.2017.v10i6.17706.

Issue

Section

Original Article(s)