HYDROGEL FORMULATION FROM CALOTROPIS GIGANTEA PLANT EXTRACT AGAINST FOOT ULCER CAUSING BACTERIA IN DIABETES
DOI:
https://doi.org/10.22159/ajpcr.2021.v14i11.37147Keywords:
Diabetes mellitus, Calotropis gigantea, Hydrogels, Formulation, HydrogelAbstract
Objective: The objective of present study was to develop hydrogel formulations loaded with Calotropis gigantea leaves extract.
Methods: The prepared hydrogel formulations were compliance with their color, odor, homogeneity, pH, and spreadability.
Results: As all the formulations were complies with the all parameters and it can be suggest as a Good antibacterial gel. It is evident that, ethanolic extract of Calotropis gigantea showed a maximum inhibitory zone against bacteria associated with foot ulcer.
Conclusions: The In vitro studies showed a quantity dependent increase in antibacterial activity against foot ulcer causing bacteria, a contraction which is higher than that produced by the control groups. These contractions were statistically significant (p<0.05), during the study with leave extract against foot ulcer causing bacteria in diabetes.
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Copyright (c) 2021 RAMACHANDRAN AM, SENTHIL PRABHU S, DEVAKUMAR J, RENGARAMANUJAM J, KARTHIK SUNDARAM S, MAHENTHIREN R, VARSHA TK
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