THE ROLE OF TURMERIC TABLETS IN ALLEVIATING INFLAMMATION AND OXIDATIVE STRESS IN CHRONIC KIDNEY DISEASE PATIENTS
DOI:
https://doi.org/10.22159/ajpcr.2025v18i12.54264Keywords:
Curcumin, Turmeric tablets, Chronic kidney disease, Inflammation, Oxidative stress, Nuclear factor erythroid 2 activation, Clinical efficacyAbstract
chronic kidney disease is a progressive condition characterized by ongoing inflammation and oxidative stress. which plays an essential role in pathophysiology and complications Recent studies highlight the possible therapeutic role of curcumin, the active compound in turmeric, in preventing these harmful processes. The effects of turmeric tablets have been evaluated in terms of their mechanism of action. Clinical efficacy and safety There is substantial evidence that curcumin supplementation is positively associated with TNF-α, IL-6, and C-reactive protein, and improving antioxidant activity by inducing erythrocyte nuclear factor2.It is associated with a reduction in inflammatory cytokines. However, curcumin's effects on traditional markers of kidney function remain controversial. Most studies reported no change in GFR or serum creatinine. Further studies will be necessary to establish an optimal dosing plan and dosing regimen to increase bioavailability and therapeutic activity. Overall, curcumin is a potential adjuvant therapy for managing inflammation and stress from Oxidative reactions in patients with chronic kidney disease and deserves further study in a clinical environment.
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