LYMPH NODE CYTOLOGY REPORTING BY “SYDNEY SYSTEM: A COMPREHENSIVE APPROACH TO LYMPH NODE FINE-NEEDLE ASPIRATION CYTOLOGY”

Authors

  • ABHISHEK SINGH Department of Pathology, Maharshi Vishwamitra Autonomous State Medical College, Ghazipur, Uttar Pradesh, India
  • SHIVENDRA DUTT SHUKLA Department of Microbiology, Maharshi Vishwamitra Autonomous State Medical College, Ghazipur, Uttar Pradesh, India.

DOI:

https://doi.org/10.22159/ajpcr.2025v18i5.54339

Keywords:

lymphadenopathies, Sydney method, Fine-needle aspiration, Lymph node cytopathology

Abstract

Objectives: The major goal of the current investigation was to categorize the lesions found in lymph nodes using the Sydney approach for reporting cytopathology of lymph nodes.

Methods: This investigation was carried out retrospectively at Maharshi Vishwamitra autonomous state medical college in Ghazipur, between January 2022 and December 2023. Total 250 patients were examined; cytopathologically assessed, and categorized using the Sydney method. Whenever feasible, a link between histopathology and clinical findings was made.

Results: Out of 250 cases, 04% (n=10) were inadequate/non-diagnostic (L1 category), 87% (n=218) were benign (L2 category), 02% (n=05) were atypical (L3 category), 2.8% (n=2.8%) were suspicious of malignancy (L4 category), and 04% (n=10) were malignant (L5 category). The sensitivity and specificity was 94.4% and 98.1%. The positive predictive value, negative predictive value, and diagnostic accuracy were 94.4%, 98.1%, and 97.1%, respectively. For L2 category, the probability of malignancy was 1.9 %, for L3 category 66.6% and for L4 and L5 was 100%.

Conclusion: The suggested reporting system intends to provide consistent recommendations on management regimens, improve communication between cytopathologists and doctors, and standardize reporting.

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References

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Published

07-05-2025

How to Cite

ABHISHEK SINGH, and SHIVENDRA DUTT SHUKLA. “LYMPH NODE CYTOLOGY REPORTING BY ‘SYDNEY SYSTEM: A COMPREHENSIVE APPROACH TO LYMPH NODE FINE-NEEDLE ASPIRATION CYTOLOGY’”. Asian Journal of Pharmaceutical and Clinical Research, vol. 18, no. 5, May 2025, pp. 87-90, doi:10.22159/ajpcr.2025v18i5.54339.

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