SOCIOCLINICAL CORRELATES AND RISK FACTORS ASSOCIATED WITH MULTIDRUGRESISTANT TUBERCULOSIS IN A TERTIARY CARE CENTER IN GANJAM, ODISHA

DEBASISH SETHY; SANJAYA KUMAR SAHOO; DURGA MADHAB SATAPATHY; ANAND KUMAR SAHU; RUDRA NARAYAN

doi:10.22159/ajpcr.2025v18i8.55324

Authors

DEBASISH SETHY Department of Community Medicine, Maharaja Krushna Chandra Gajapati Medical College, Berhampur, Odisha, India
SANJAYA KUMAR SAHOO Department of Community Medicine, Shri Jagannath Medical College, Puri, Odisha, India.
DURGA MADHAB SATAPATHY Department of Community Medicine, Maharaja Krushna Chandra Gajapati Medical College, Berhampur, Odisha, India.
ANAND KUMAR SAHU Department of Community Medicine, Maharaja Krushna Chandra Gajapati Medical College, Berhampur, Odisha, India.
RUDRA NARAYAN Department of Community Medicine, Maharaja Krushna Chandra Gajapati Medical College, Berhampur, Odisha, India.

DOI:

https://doi.org/10.22159/ajpcr.2025v18i8.55324

Keywords:

Multidrug-resistant tuberculosis, Socioclinical profile, Ganjam, Tuberculosis, Drug resistance, Public Health.

Abstract

Objectives: The purpose of the study is to assess the socioclinical profile of multidrug-resistant tuberculosis (MDR-TB) cases admitted to a tertiary care hospital in Ganjam.

Methods: A cross-sectional study was conducted among the MDR-TB patients admitted to the indoor DR-TB ward of the Department of Pulmonary Medicine of MKCG Medical College and Hospital, Berhampur, from October 2023 to October 2024. Data were collected with the help of a questionnaire, which comprised information on socioclinical characteristics of the study participants. The data were tabulated by MS-Excel v.21 and then analyzed using statistical software like JAMOVI v.2.6.13.

Results: Among 103 MDR-TB patients who consented to participate in the study, the majority were males of 20–40 years. Mostly, study participants were educated in primary school, belonged to the lower-middle class, and engaged in semi-skilled occupations. 93% of the patients admitted presented with cough followed by expectoration (69%), fever (68%), vomiting (67%), hemoptysis (35%), etc. Among the co-morbidities reported, the majority were chronic obstructive pulmonary disease (COPD), followed by diabetes mellitus, hypertension, and HIV/AIDS, respectively.

Conclusion: MDR-TB remains a major health problem in Ganjam, which is mainly influenced by low socioeconomic status, conditions like overcrowding, and various clinical conditions such as COPD, hypertension, HIV, and diabetes mellitus. These comorbidities complicate the clinical management of MDR-TB and may influence treatment outcomes. A comprehensive, patient-centered approach involving the diagnosis and management of coexisting illnesses is essential for achieving better therapeutic results.

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