DEVELOPMENT OF FILM COATED ORAL DOSAGE FORM OF ACAMPROSATE CALCIUM

Authors

  • ANKITA PARDESHI Department of Quality Assurance, Tapi valley Education Society’s Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur, Maharashtra, India.
  • AMOL PATIL Department of Pharmacology, Tapi valley Education Society’s Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur, Maharashtra, India https://orcid.org/0009-0000-5185-9948
  • SACHIN RANE Department of Pharmaceutical Chemistry, Tapi valley Education Society’s Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur, Maharashtra, India.
  • JESIKA RANE Department of Quality Assurance, Tapi valley Education Society’s Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur, Maharashtra, India

DOI:

https://doi.org/10.22159/ajpcr.2026v19i3.56908

Keywords:

Acamprosate calcium, Film-coated tablets, Drug delivery system

Abstract

Objective: The present work is directed toward the development of film coated oral dosage form (tablet), which will extend the release of Acamprosate calcium.

Methods: Film-coating tablet containing Acamprosate calcium was prepared by the direct compression method.

Results: The hardness, drug content, disintegration, and dissolution profile of Acamprosate calcium batch F6 considered as optimized batch. This batch showed dissolution of the drug at 180 min about 94%. Drug content of optimized batch was 99.7%, Hardness and thickness of optimized batch (F6) were found to be 9.3–11.3N and 5.57–5.69 mm, respectively.

Conclusion: Prepared Film-coated tablets of Acamprosate calcium have extended release as expected.

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Published

07-03-2026

How to Cite

ANKITA PARDESHI, et al. “DEVELOPMENT OF FILM COATED ORAL DOSAGE FORM OF ACAMPROSATE CALCIUM”. Asian Journal of Pharmaceutical and Clinical Research, vol. 19, no. 3, Mar. 2026, pp. 140-3, doi:10.22159/ajpcr.2026v19i3.56908.

Issue

Vol 19 Issue 3 March 2026

Section

Original Article(s)

Copyright (c) 2026 Amol Pundlik Patil, ANKITA PARDESHI, SACHIN RANE, JESIKA RANE

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