PSYCHOSOCIAL FACTORS ASSOCIATED WITH ABSTINENCE AND RELAPSE IN ALCOHOL DEPENDENCE: A CROSS-SECTIONAL COMPARATIVE STUDY

Authors

  • M TABITHA SHARON Department of Pharmacy Practice, VIPW, Vijayawada, Andhra Pradesh, India. https://orcid.org/0000-0003-4797-370X
  • S SARATH AJAY KUMAR Department of Psychiatry, Government General Hospital, Vijayawada, Andhra Pradesh, India. https://orcid.org/0009-0006-8795-895X
  • B ROSHNI Department of Pharmacy Practice, VIPW, Vijayawada, Andhra Pradesh, India. https://orcid.org/0009-0009-1063-5636
  • P JAHNAVI Department of Pharmacy Practice, VIPW, Vijayawada, Andhra Pradesh, India.
  • CH. NAGA SIVANI Department of Pharmacy Practice, VIPW, Vijayawada, Andhra Pradesh, India
  • K PADMALATHA Department of Pharmacology, VIPW, Vijayawada, Andhra Pradesh, India. https://orcid.org/0000-0002-2728-9073

DOI:

https://doi.org/10.22159/ajpcr.2026v19i3.57345

Keywords:

Alcohol dependence, Relapse, Coping, Self-efficacy, Social support,, Stress

Abstract

Objectives: This study evaluated psychosocial predictors of relapse and abstinence in alcohol-dependent individuals using standardized psychosocial assessment tools.

Methods: A cross-sectional study was conducted among 100 Diagnostic and Statistical Manual of Mental Disorders, 5th Edition–diagnosed alcohol-dependent patients (50 relapse; 50 abstinent). Four validated scales – Coping Behavior Inventory (CBI), Alcohol Abstinence Self-Efficacy Scale (AASES), Multidimensional Scale of Perceived Social Support (MSPSS), and Social Readjustment Rating Scale (SRRS) – were administered. Continuous predictors were standardized (z-scores). A single logistic regression model predicted relapse.

Results: Maladaptive coping was the strongest predictor of relapse (odds ratio [OR] = 30.98; 95% confidence interval [CI]: 7.99–120.16; p<0.001). Higher self-efficacy was protective (OR=0.34; 95% CI: 0.16–0.70; p=0.003). Higher perceived social support predicted relapse (OR=3.61; 95% CI: 1.52–8.58; p=0.004). Stress showed borderline significance (OR=2.06; p=0.055). Model fit was strong (Nagelkerke R2=0.54).

Conclusion: Coping, self-efficacy, social support, and stress significantly influence relapse risk. Psychosocial interventions enhancing coping and self-efficacy and modifying maladaptive family support may reduce relapse.

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References

1. World Health Organization, Ray R. Global Status Report on Alcohol and Health 2023. Geneva: World Health Organization, National Survey Drug Abuse; 2004.

2. Ministry of Social Justice and Empowerment, Government of India. Magnitude of Substance Use in India 2019. New Delhi: Government of

India; 2019.

3. Hunt WA, Barnett LW, Branch LG. Relapse rates in addiction programs. J Clin Psychol. 1971;27:455-6.

4. Litman GK, Eiser JR, Rawson NS, Oppenheim AN. Determinants of coping behaviour in alcoholics. Br J Addict. 1983;78:269-76.

5. Mattoo SK, Malhotra R. Self-efficacy scale: Hindi translation and factor structure. Indian J Clin Psychol. 1998;25:154-8.

6. Zimet GD, Dahlem NW, Zimet SG, Farley GK. The multidimensional scale of perceived social support. J Pers Assess. 1988;52(1):30-41. doi: 10.1207/s15327752jpa5201_2

7. Singh G, Verma HC, Gupta SC. Stressful life events and relapse in alcohol dependence. Indian J Psychiatry. 1984;26:107-14.

8. Mattoo SK, Chakrabarti S, Anjaiah M. Psychosocial factors associated with relapse in men with alcohol or opioid dependence. Indian J Med Res. 2009;130(6):702-8. PMID 20090130

9. Sureshkumar K, Kailash S, Dalal PK, Reddy MM, Sinha PK. Psychosocial factors associated with relapse in patients with alcohol dependence. Indian J Psychol Med. 2017;39:312-5.

10. Nattala P, Murthy P, Thennarasu K, Benegal V. Family-focused relapse prevention for alcohol dependence. J Stud Alcohol Drugs. 2010;71:581-7.

11. Kelly JF, Urbanoski KA. Youth recovery contexts: The incremental effects of recovery capital. Alcohol Res. 2012;34:391-403.

12. Witkiewitz K, Marlatt GA. Relapse prevention for alcohol and drug problems. J Cogn Psychother. 2004;18:211-28.

13. McKay JR. Studies of factors in relapse to alcohol, drug and nicotine use: A critical review of methodologies and findings. J Stud Alcohol. 1999;60(4):566-76. doi: 10.15288/jsa.1999.60.566, PMID 10463814

14. Kumar N, Gupta N, Kishore J. Kuppuswamy socioeconomic status scale: Updated for 2023. Indian J Pediatr. 2023;90:1-3.

15. Kelly JF, Hoeppner BB, Stout RL, Pagano ME. Expressed emotion and relapse in substance use disorders. Addict Behav. 2021;117:106846.

16. Bose S, Jena R. Psychosocial predictors of relapse in alcohol dependence. Asian J Psychiatry. 2022;72:103113.

17. Das SK, Balakrishnan V, Vasudevan DM. Stress vulnerability and relapse in alcohol dependence. Indian J Psychol Med. 2023;45:126-33.

18. Sahu A, Patel P. Coping strategies among patients with substance use disorder. Int J Appl Pharm. 2020;12:45-9.

19. Sethi B, Mazumder R. Psychosocial factors associated with alcohol dependence. Int J Appl Pharm. 2019;11(1):89-93. doi: 10.22159/ ijap.2019v11i1.29082

20. Sharma P, Gupta R. Stress and relapse patterns in alcohol dependence. Int J Pharm Pharm Sci. 2018;10:120-4.

21. Chatterjee A, Singh N. Predictors of relapse in alcohol dependence. Int J Curr Pharm Res. 2019;11:108-12.

Published

07-03-2026

How to Cite

M TABITHA SHARON, et al. “PSYCHOSOCIAL FACTORS ASSOCIATED WITH ABSTINENCE AND RELAPSE IN ALCOHOL DEPENDENCE: A CROSS-SECTIONAL COMPARATIVE STUDY”. Asian Journal of Pharmaceutical and Clinical Research, vol. 19, no. 3, Mar. 2026, pp. 108-10, doi:10.22159/ajpcr.2026v19i3.57345.

Issue

Vol 19 Issue 3 March 2026

Section

Original Article(s)

Copyright (c) 2026 Dr. Tabitha Sharon. M, Dr. S Sarath Ajay Kumar, B. Roshini, P Jahnavi, Nagasivani Chilukuri, Dr. Padmalatha Kantamaneni

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