A DIAGNOSTIC DILEMMA: RECURRENT HYPOKALEMIC WEAKNESS SECONDARY TO SJOGREN'S SYNDROME (A DRTA EFFECT)

MAULIK KUMAR KARPATIYA; SANJAYKUMAR RATHWA; PRAYANS SHAH; PRATIKSHA RATHWA

doi:10.22159/ijcpr.2025v17i2.6071

Authors

MAULIK KUMAR KARPATIYA Department of Medicine, SBKS Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Pipariya, Vadodara, India https://orcid.org/0009-0003-0394-4824
SANJAYKUMAR RATHWA Department of Medicine, SBKS Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Pipariya, Vadodara, India
PRAYANS SHAH Department of Medicine, SBKS Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Pipariya, Vadodara, India https://orcid.org/0009-0005-4317-3571
PRATIKSHA RATHWA Department of Dermatology Venereology and Leprosy, SBKS Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Pipariya, Vadodara, India https://orcid.org/0009-0007-1746-8303

DOI:

https://doi.org/10.22159/ijcpr.2025v17i2.6071

Keywords:

Sjogren’s syndrome (SS), Hypokalemic paralysis, Renal tubular acidosis, Nephrolithiasis

Abstract

Renal involvement occurs in approximately 5% of patients with Sjogren’s syndrome (SS). Renal lesions that predominate are tubulointerstitial nephritis and membranoproliferative glomerulonephritis. We report the case of a 50-year-old female who presented with weakness of lower limbs. A diagnosis of distal renal tubular acidosis type 1 (DTA1) secondary to SS was made, discovered in view of hypokalemic paralysis. The patient was treated symptomatically with injectable potassium chloride sodium bicarbonate. Corticosteroid and hydroxychloroquine were used to treat SS. The patient improved with correction of acidosis and hypokalemia.

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