PREVALENCE OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS FROM CLINICAL SAMPLES IN A TERTIARY CARE HOSPITAL
DOI:
https://doi.org/10.22159/ijcpr.2025v17i3.55071Keywords:
Staphylococcus aureus, Methicillin-resistant staphylococcus aureus, PrevalenceAbstract
Objectives: The present research is mainly focussed on the prevalence of S. aureus MRSA strains isolated from various clinical samples in a tertiary care teaching hospital.
Methods: This is a prospective study conducted in the department of Microbiology, tertiary care teaching hospital, Telangana during the period from Jan 2024 to Feb 2025. S. aureus isolates isolated from various clinical specimens like pus, wound swab, aspirates, blood, urine, and other body fluids were tested for the presence of Staphylococcus aureus. All the collected patient samples were processed aseptically using a standard microbiology protocol of culture and sensitivity. The isolates will then be subjected to susceptibility testing by Kirby-Bauer’s disc diffusion method on Mueller-Hinton agar plates as per CLSI guidelines.
Results: Among 529 culture-positive cases, 23 strains (4.3%) were MRSA and 49 strains (9.2%) were MSSA. Among the prevalence of S. aureus studied in different age groups, maximum number of cases (29.47%) were reported in the age group of>60 y of age. MRSA and MSSA incidence of 60.8% and 57.14% was seen more in males than females. All the 23 strains of MRSA were resistant to cefoxitin. Most of the MRSA were sensitive to gentamycin, amikacin, meropenem, vancomycin, linezolid, clindamycin. All the 23 strains were sensitive to linezolid and vancomycin. The sensitivity to Vancomycin was confirmed by Van E strip method.
Conclusion: The findings of the current study showed the lowest prevalence of MRSA in the study population 4.3%.
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