POLYMERIC NANOCARRIERS IN THERAPEUTIC DELIVERY: CURRENT TRENDS AND FUTURE HORIZONS

ANJALI MISHRA; APOORVA KUMARI; GAURI BARAIK; ANAMIKA PALAK

doi:10.22159/ijcpr.2025v17i4.7041

Authors

ANJALI MISHRA Department of Pharmacy, Sarala Birla University, Mahilong, Ranchi, Jharkhand, India https://orcid.org/0000-0001-7676-7978
APOORVA KUMARI Department of Pharmaceutical Sciences, Jharkhand Rai University, Namkum, Ranchi, Jharkhand, India
GAURI BARAIK Department of Pharmaceutical Sciences, Jharkhand Rai University, Namkum, Ranchi, Jharkhand, India
ANAMIKA PALAK Department of Pharmaceutical Sciences, Jharkhand Rai University, Namkum, Ranchi, Jharkhand, India

DOI:

https://doi.org/10.22159/ijcpr.2025v17i4.7041

Keywords:

Polymeric nanoparticles, Nanocarriers, Dendrimers, Sustained release, Chitosan, Sodium alginate

Abstract

This detailed review on ‘Polymeric nanocarriers’, aims to provide an in-depth understanding of polymeric nano entities as a novel and efficient platform for drug delivery, with a focus on improving therapeutic precision and minimizing side effects. The study examines the design principles, drug loading capabilities, and release profiles of polymeric nanoparticles, along with their mechanisms for passive and active targeting. It also highlights their current applications in areas such as cancer therapy, gene delivery, and vaccination, while addressing the key challenges, including biocompatibility, scalability, and regulatory approval. Future trends such as stimuli-responsive systems and integration with artificial intelligence are also discussed. Polymeric nanoparticles offer versatile and highly tunable systems for controlled and targeted drug delivery. With continued advancements in material science and nanotechnology, they hold significant promise for transforming conventional therapies and advancing the field of personalized medicine, despite existing barriers that must still be addressed for widespread clinical use.

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