ANTI-AGING DRUGS: A COMPREHENSIVE PHARMACOLOGICAL ANALYSIS

SATYENDRA NARAYAN TIWARI; TUSHAR C. BAHETI; RAJESH C. S.; RAJ K. SHARMA

doi:10.22159/ijcpr.2025v17i5.7047

Authors

SATYENDRA NARAYAN TIWARI Department of Pharmacology, Chirayu Medical College and Hospital, Chirayu University, Bhopal, (M. P.) India
TUSHAR C. BAHETI Department of Pharmacology, Chirayu Medical College and Hospital, Chirayu University, Bhopal, (M. P.) India
RAJESH C. S. Department of Pharmacology, Sri Siddhartha Institute of Medical Sciences & Research Centre, T.Begur
RAJ K. SHARMA Department of Pharmacology, Chirayu Medical College and Hospital, Chirayu University, Bhopal, (M. P.) India

DOI:

https://doi.org/10.22159/ijcpr.2025v17i5.7047

Keywords:

Anti-aging, Antioxidants, Senolytics, Telomerase activators and Hormone replacement therapies

Abstract

Objective: The primary aim of this study is to provide a comprehensive analysis of the pharmacological interventions targeting the mechanisms of aging. 1) To categorize and describe the different classes of anti-aging drugs, including antioxidants, senolytics, telomerase activators, and hormone replacement therapies. 2) To analyze recent research findings on anti-aging therapeutics. 3) To analyze growth trajectory of anti-aging drugs globally.

Methods: This analysis was conducted by systematically searching scientific databases, including PubMed, Scopus, and Web of Science, for articles published between 2000 and 2025 related to anti-aging drugs and their mechanisms of action.

Results: The research analysis identified ten major classes of anti-aging drugs, with senolytics and caloric restriction mimetics showing the most promise. Emerging therapies like NAD⁺ precursors, stem cell treatments, and antibody-based approaches are under active investigation. The global anti-aging drug market is growing rapidly, driven by innovation and increased demand for longevity solutions.

Conclusion: The exploration of anti-aging drugs through a pharmacological lens highlights the significant advancements and challenges in this field.

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