OVERVIEW ON GUT MICROBIOME

HARINI P; DINESH S; RADHA PALANISWAMY

doi:10.22159/ijms.2025v13i3.54218

Authors

HARINI P Department of Biotechnology, Dr. N.G. P Arts and Science College, Coimbatore, Tamil Nadu, India. https://orcid.org/0009-0001-9410-7495
DINESH S Department of Biotechnology, Dr. N.G. P Arts and Science College, Coimbatore, Tamil Nadu, India.
RADHA PALANISWAMY Department of Biotechnology, Dr. N.G. P Arts and Science College, Coimbatore, Tamil Nadu, India

DOI:

https://doi.org/10.22159/ijms.2025v13i3.54218

Keywords:

gastrointestinal, gut microbiota, metabolics, microbiome, host

Abstract

The assemblage of eukaryotic and prokaryotic kingdom inhabiting the gastrointestinal system is termed as the microbiota and developed alongside human and other eukaryotic systems for millennia, developing a mutually complicated and advantageous connection. The digestive system is home to an estimated number of microorganisms surpassing 1014, which is approximately greater then than the plethora of human cells and more than hundredfold times greater than the amount of genetic information found in the human gene. The microbiome is the native population of microbes (microbiota) in the host and develops along with it. The perception that the microbes predominantly present in human system gives vital environmental functions that act as a welfare for the whole microbial host system, therefore the mass fundamental development. The human gut microbiome is composed of variants of number of bacteria. Particularly, this gut environment depicts tons of bacterial cells which are important factors that manage gut immune system. The metabolic activities such as immunity, nutrition absorption, and digestion are interlinked with this microbial community. Studies developed that abnormalities in the gut microbiome are result of diseases including obesity, inflammatory lung disease, and CVS diseases, carcinoma during advent studies. The assemblage of bacteria, Archaea, and eukarya inhabiting the gastrointestinal tract is known as the microbiota and developed alongside the host for millennia, establishing a mutually complex and advantageous relationship. This review focuses on the overall view of the microbe in gut.

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