ROLE OF PLANT-BASED FLAVONOIDS AS DRUG CANDIDATES FOR INFLAMMATORY BOWEL DISEASE-A SHORT REVIEW

SAMRITI FAUJDAR; PRABHA HULLATTI; NABARUN MUKHOPADHYAY; A. P. BASAVARAJAPPA; SARASWATI PATEL

doi:10.22159/ijpps.2025v17i6.53851

Authors

SAMRITI FAUJDAR Department of Pharmacy, Banasthali Vidyapith, Rajasthan, India https://orcid.org/0009-0005-8405-283X
PRABHA HULLATTI Department of Pharmacy, Banasthali Vidyapith, Rajasthan, India
NABARUN MUKHOPADHYAY Department of Chemical Sciences (Natural Products), National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana, India https://orcid.org/0000-0002-8851-9485
A. P. BASAVARAJAPPA Department of Pharmacology, Bapuji Pharmacy College, Davangere, Karnataka, India https://orcid.org/0009-0006-0377-9082
SARASWATI PATEL Department of Pharmacology, Saveetha College of Pharmacy, Thandalam, Chennai, Tamil Nadu, India https://orcid.org/0000-0002-8500-2421

DOI:

https://doi.org/10.22159/ijpps.2025v17i6.53851

Keywords:

Plant-based flavonoids, Phytoconstituents, Drugs, Inflammatory bowel disease

Abstract

Inflammatory Bowel Disease (IBD) is a chronic disorder caused due to several factors. Out of these, inflammation is one of the major causative factors, and several inflammatory markers, like pro-inflammatory cytokines enzymes play an essential role in the progression and development of IBD. The existing therapies against IBD have severe adverse effects, and drug resistance can also occur. Hence, novel therapies against IBD need to be developed for the treatment and prevention of IBD. Natural products, specifically flavonoids, can be an excellent alternative to get better therapeutic efficacy. Hence, flavonoids can be utilized more bitterly as a drug candidate for IBD. Our review work mainly discussed the potential flavonoids and their role in treating IBD and also focussed on it by inhibiting inflammatory markers.

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