PEDIOCIN PRODUCTION BY PEDIOCOCCUS ACIDILACTICI IN CONTINUOUS MODE USING MEAT PROCESSING WASTE
DOI:
https://doi.org/10.22159/ijpps.2025v17i7.55366Keywords:
Pediocin, Continuous reactor, Pediococcus acidilactici, Mathematical modelAbstract
Objective: The production of pediocin by Pediococcus acidilactici has been studied on a bioreactor in continuous mode. Meat processing waste (MPW) has been used as a growth medium. Different dilution rate has been attempted in continuous process to maximize the pediocin production.
Methods: The continuous fermentation process was carried out at various dilution rates, ranging from 0.075 h-1 to 0.15 h-1. A mathematical model has been developed for simulation of the continuous process.
Results: The maximum pediocin activity was observed 2743 AU/ml in continuous cultures at dilution rate of 0.075 h-1. The values of correlation coefficient (R2) were in the range of 0.94 to 0.98. The predicted model was well validated.
Conclusion: The continuous pediocin production could be possible for large-scale application.
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