FORMULATION AND EVALUATION OF POLYHERBAL SKIN-CARE CREAM CONTAINING LIQUORICE AND ALOE

Authors

  • ARPIT MISHRA Department of Pharmacy, Shri G. S. Institute of Technology and Science, 23-Park Road, Indore-452003, Madhya Pradesh, India
  • ARUN SHERKE Department of Pharmacy, Shri G. S. Institute of Technology and Science, 23-Park Road, Indore-452003, Madhya Pradesh, India
  • BHANU LOHARE Department of Pharmacy, Shri G. S. Institute of Technology and Science, 23-Park Road, Indore-452003, Madhya Pradesh, India https://orcid.org/0009-0006-7252-7188
  • REENA SONI Department of Pharmacy, Shri G. S. Institute of Technology and Science, 23-Park Road, Indore-452003, Madhya Pradesh, India https://orcid.org/0009-0006-0971-7560

DOI:

https://doi.org/10.22159/ijpps.2025v17i12.55508

Keywords:

Liquorice extract, Aloe vera gel, Skin care, Polyherbal cream

Abstract

Objective: The present study focuses on the formulation and evaluation of a polyherbal skin care cream incorporating Liquorice (Glycyrrhiza glabra) extract and Aloe vera (Aloe barbadensis) gel, aimed to enhance skin health through natural and safe ingredients.

Methods: The cream was prepared by using slab technique/extemporaneous method for geometric and homogenous mixing of all the excipients and the herbal extract and prepared formulation evaluated for various parameters such as color, odor, consistency, homogeneity, pH, spreadability, viscosity, irritancy test, washability test, dye test, phase separation test.

Results: The evaluation parameters are coming under this heading physical parameter like color was faint brown and odor was pleasant, consistency was smooth and the state was semisolid. pH of the cream was 6.82, spread ability was 15.92 g. cm/s, wash ability was easily washable, the cream was non-irritant, viscosity of the formulated cream was 3502.67cps and no phase separation was observed during storage of polyherbal cream and passed the stability study test.

Conclusion: The developed polyherbal cream formulation possessed all desired quality attributes and physico-chemical properties. Hence, it can be concluded that the cream was stable and can be safely used topically for skin care.

Downloads

Download data is not yet available.

References

1. Roy J, Pal A, Chakraborty S. Herbal creams: an overview. Int J Health Sci Res. 2024 Jul;14(7):136-44. doi: 10.52403/ijhsr.20240717.

2. Dongare PN, Bakal DR, Ajmire PV, Patinge PA, More MP, Manwar DJ. An overview on herbal cosmetics and cosmeceuticals. IJPSRR. 2021;68(1):75-8. doi: 10.47583/ijpsrr.2021.v68i01.013.

3. Asl MN, Hosseinzadeh H. Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytother Res. 2008 Jun;22(6):709-24. doi: 10.1002/ptr.2362, PMID 18446848.

4. Tian M, Yan H, Row KH. Extraction of glycyrrhizic acid and glabridin from licorice. Int J Mol Sci. 2008 Apr;9(4):571-7. doi: 10.3390/ijms9040571, PMID 19325770.

5. Mayuri S, Pawar VK. Study of potential antitussive activity of Glycyrrhiza glabra granules by using a cough model induced by sulphur dioxide gas in mice. Asian J Pharm Clin Res. 2019 Oct;12(10):262-7. doi: 10.22159/ajpcr.2019.v12i10.33967.

6. Boyko N, Tkachev A, Kovalenko A, Pisarev D, Kuznietsova V, Sushchuk N. Phytochemical, microbiological and technological studies in the field of obtaining a hydroalcoholic extract with antimicrobial activity from the liquorice root. Asian J Pharm Clin Res. 2019;12(1):403-7. doi: 10.22159/ajpcr.2019.v12i1.30454.

7. Fu B, Li H, Wang X, Lee FS, Cui S. Isolation and identification of flavonoids in licorice and a study of their inhibitory effects on tyrosinase. J Agric Food Chem. 2005 Sep 21;53(19):7408-14. doi: 10.1021/jf051258h, PMID 16159166.

8. Chandra VC, Nuraeny N, Wahyuni IS. Anti-inflammatory potential of Aloe vera in oral mucositis therapy: systematic review. Int J App Pharm. 2022 Jul;14:22-7. doi: 10.22159/ijap.2022.v14ti.21.

9. Budiman A, Khoerunnisa R, Qoriah TA. Wound healing test of Piper betle leaf extract and Aloe vera in gel preparation. Int J App Pharm. 2018 Mar;10(3):86-91. doi: 10.22159/ijap.2018v10i3.24408.

10. Vyas J, Rana S. Antioxidant activity and biogenic synthesis of selenium nanoparticles using the leaf extract of Aloe vera. Int J Curr Pharm Sci. 2017 Jul;9(4):147-52. doi: 10.22159/ijcpr.2017v9i4.20981.

11. Huynh A, Abou Dahech MS, Reddy CM, O Neil GW, Chandler M, Baki G. Alkenones a renewably sourced biobased wax as an SPF booster for organic sunscreens. Cosmetics. 2019 Feb;6(1):11. doi: 10.3390/cosmetics6010011.

12. Verallo Rowell VM, Dillague KM, Syah Tjundawan BS. Novel antibacterial and emollient effects of coconut and virgin olive oils in adult atopic dermatitis. Dermatitis. 2008 Nov-Dec;19(6):308-15. doi: 10.2310/6620.2008.08052, PMID 19134433.

13. Thiele JJ, Ekanayake Mudiyanselage S. Vitamin E in human skin: organ-specific physiology and considerations for its use in dermatology. Mol Aspects Med. 2007;28(5-6):646-67. doi: 10.1016/j.mam.2007.06.001, PMID 17719081.

14. Walters KA, Roberts MS, editors. Dermatologic cosmeceutic and cosmetic development. Boca Raton: CRC Press; 2007. doi: 10.3109/9780849375903.

15. Arct J, Pytkowska K. Flavonoids as components of biologically active cosmeceuticals. Clin Dermatol. 2008 Jul-Aug;26(4):347-57. doi: 10.1016/j.clindermatol.2008.01.004, PMID 18691514.

16. Al Waili N, Salom K, Al Ghamdi AA. Honey for wound healing, ulcers and burns; data supporting its use in clinical practice. Scientific World Journal. 2011;11:766-87. doi: 10.1100/tsw.2011.78, PMID 21479349.

17. Ajagannanavar SL, Battur H, Shamarao S, Sivakumar V, Patil PU, Shanavas P. Effect of aqueous and alcoholic licorice (Glycyrrhiza glabra) root extract against streptococcus mutans and Lactobacillus acidophilus in comparison to chlorhexidine: an in vitro study. J Int Oral Health. 2014 Jul;6(4):29-34. PMID 25214729, PMCID PMC4148569.

18. Rudra A, Shoeb A. Development formulation and evaluation of Aloe vera tooth gel: an antimicrobial study. Int J Pharm Pharm Sci. 2023 Oct;15(10):6-12. doi: 10.22159/ijpps.2023v15i10.48765.

19. Sahu PK, Giri DD, Singh R, Pandey P, Gupta S, Shrivastava AK. Therapeutic and medicinal uses of Aloe vera: a review. Pharmacol Pharm. 2013 Nov;4(8):599-610. doi: 10.4236/pp.2013.48086.

20. Rabade VS, Pawar MS, Titarmare GK. Formulation and evaluation of polyherbal cold cream. Int J Pharm Res Schol. 2020;9(4):25-31.

21. Gunjal PT, Shinde MB, Gharge VS, Pimple SV, Gurjar MK, Shah MN. Design development and optimization of S (-) atenolol floating sustained release matrix tablets using surface response methodology. Indian J Pharm Sci. 2015;77(5):563-72. doi: 10.4103/0250-474X.169036, PMID 26798171.

22. Rajvanshi A, Sharma S, Khokra SL. Formulation and evaluation of Cyperus rotundus and Cucumis sativus-based herbal face cream. Pharmacol Online. 2011;2(1):1238-44.

23. Chandrasekar R, Sivagami B. Formulation and evaluation of a polyherbal skin care cream containing neem and Tulsi. Res J Top Cosmet Sci. 2018;9(1):25-32. doi: 10.5958/2321-5844.2018.00006.7.

24. Chavan P, Kalshetti M, Navindgikar N. Formulation and evaluation of polyherbal cream. Int J Curr Pharm Sci. 2020 Jul;12(4):75-7. doi: 10.22159/ijcpr.2020v12i4.39086.

25. Babu R, Semwal A, Sharma S. Formulation and evaluation of polyherbal cream. World J Pharm Res. 2022 Sep;11(8):646-60. doi: 10.20959/wjpr20228-24274.

26. Shivathaya N, Surve R, Sawant R, Khot S, Biradar K, Verma R. Formulation and in vitro evaluation of ethanolic extract of polyherbal face cream. Int J Curr Pharm Sci. 2022 Mar;14(2):41-7. doi: 10.22159/ijcpr.2022v14i2.1950.

27. Nikam A, Magdum C. Extraction preparation and evaluation of phyllanthus urinaria extract as an antifungal cream. Asian J Res Chem. 2021;14(5):353-6. doi: 10.52711/0974-4150.2021.00060.

28. Ahmed AA, Nath B. Formulation and in vitro evaluation of poly-herbal anti-ageing face cream of Coriandrum sativum and rose hip oil. Int J Curr Pharm Sci. 2017 Jul;9(4):75-8. doi: 10.22159/ijcpr.2017v9i4.20961.

Published

01-12-2025

How to Cite

MISHRA, ARPIT, et al. “FORMULATION AND EVALUATION OF POLYHERBAL SKIN-CARE CREAM CONTAINING LIQUORICE AND ALOE”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 17, no. 12, Dec. 2025, pp. 17-21, doi:10.22159/ijpps.2025v17i12.55508.

Issue

Section

Original Article(s)

Similar Articles

<< < 46 47 48 49 50 > >> 

You may also start an advanced similarity search for this article.