Vol 17, Issue 4 (Jul-Aug), 2025

Published: 07-07-2025

Review Article(s)

THE SAFETY OF EXCIPIENTS AS A KEY FACTOR IN SUCCESSFUL DRUG DEVELOPMENT

NATALIA DEMINA, ELENA BAKHRUSHINA, MARIA ANUROVA, SALMA ABUELEZ, IRINA ZUBAREVA, IVAN KRASNYK

1-9
BIBLIOMETRIC ANALYSIS OF DRUG RESISTANCE BIOMARKERS IN BREAST CANCER (2020-2025)

EVA NURSOLEHA, WAHYU UTAMI

10-18
ADVANCING CURCUMIN APPLICATIONS IN HEPATOCELLULAR CARCINOMA: INSIGHTS INTO PHARMACOKINETICS, PHARMACODYNAMICS AND NANODELIVERY SYSTEMS

RESHMA T. MATE, ANURADHA N. CHIVATE, NAMDEO R. JADHAV, NIRANJAN D. CHIVATE

19-29
METAL–ORGANIC FRAMEWORKS OVERVIEW: STATE OF THE ART

REEM MOHSIN KHALAF AL-UOBODY, HAYDER A. HAMMOODI, AMIRA AMIN

30-37
LIPID-POLYMER HYBRID NANOPARTICLES AND SILICA-BASED HYBRID NANOPARTICLES FOR CANCER TREATMENT

ANJANA A. KAILAS, ANNAMALAI RAMA, BHAUTIK LADANI, INDUJA GOVINDAN, K. A. ABUTWAIBE, ANUP NAHA

38-50
INNOVATIVE STRATEGIES FOR IMPROVING PROBIOTIC VIABILITY USING AVOCADO-BASED PREBIOTICS AND NANOTECHNOLOGY

JATIN M., BISHOP ADHIKARI, ALIN BOSE J., PIYUSH KUMAR, RAMAN RAJESH KUMAR

51-65
3D PRINTING TECHNOLOGIES IN THE DEVELOPMENT OF A BIORELEVANT IN VITRO MODEL OF THE NASAL CAVITY: NEW STEP OF INTRANASAL DRUGS QUALITY ASSESSMENT

IOSIF MIKHEL, ELENA BAKHRUSHINA, SALMA ABUELEZ, KSENIYA EREMEEVA, XI YANG, VALERIY SVISTUSHKIN, OLGA I. STEPANOVA, IVAN I. KRASNYUK JR., GLEB ZHEMERIKIN, IVAN I. KRASNYUK

66-76
APPLICATION OF INHALATION THERAPEUTICS FOR LUNG CANCER TREATMENT: AN UPDATED REVIEW

PADIYAR NEHA, BISHT TANUJA, TYAGI YOGITA, JHAKMOLA VIKAS

77-90
BEYOND NEEDLES: INNOVATIONS IN TRANSDERMAL ANTIBIOTIC DELIVERY SYSTEMS

RAWAND M. DAGHMASH, SHEREEN M. ASSAF

91-116
RECENT INNOVATIONS IN MICROFABRICATION TECHNIQUES FOR ENHANCED MICROFLUIDIC CHIP PERFORMANCE IN DRUG DEVELOPMENT

ANKANA ROY, VASANTHARAJU SG, MUDDUKRISHNA BS, BHARGAV ERANTI, SACHIN DATTRAM PAWAR, GUNDAWAR RAVI

117-126

Original Article(s)

PREPARATION, EVALUATION AND IN VIVO STUDIES OF NOVEL HERBAL LIPOGEL OF OCIMUM TENUIFLORAM (L.) EXTRACT FOR ACNE TREATMENT

VANDANA SINGH, RAVINDER VERMA, VINEET MITTAL, DEEPAK KAUSHIK

127-144
ASSEESSMENT OF CELLULAR TOXICITY ON CANCER CELL LINES USING CAPSAICIN-LOADED PLGA NANOBUBBLES

HEMA KUMAR A. V., CHAMAKURI KANTLAM

145-151
HYPOTHETICAL IN VIVO BEHAVIOR OF CARBAMAZEPINE TABLETS FROM IN VITRO RELEASE DATA OF USP APPARATUS II AND IV AND DISSOLUTION MEDIA OF PHYSIOLOGICAL RELEVANCE

FELIPE DINO REYES RAMIREZ, YAMIR ALI VERA ANGELES, JOSE RAUL MEDINA LOPEZ

152-158
ISOLATION, MANUFATURE AND QUALITATIVE TEST OF CELLULOSE MICROCRYSTALLIZATION POWDER FROM KETAPANG LEAVES (TERMINALIA CATAPPA L.) USING CHEMICAL DELIGNIFICATION AND HYDROLISIS METHODS

YUSPA, MUHAMMAD, FATIMAH, NUR MAULIDAH, RA’IDAH LUTHFIA, YULIANITA PRATIWI INDAH LESTARI

159-165
SCREENING, DESIGN AND CHARACTERIZATION OF ALGAE-BASED TOPICAL DOSAGE FORM AS A REMEDY FOR DIGITAL AGEING

FATIMA SANJERI DASANKOPPA, REVATI DHARAMPAL SAGARE, MEGHA N. SUREBAN, HASANPASHA N. SHOLAPUR, ARUNKUMAR GUNDAIAH RAMESH, VIJAYAKUMAR MURUGESAN

166-177
DEVELOPMENT AND OPTIMIZATION OF ARNEBIN-1 LOADED THERMOSENSITIVE HYDROGEL FOR WOUND HEALING

RAHUL GODGE, KAILAS BARDE, ONKAR PAWAR, SANTOSH DIGHE

178-192
OPTIMIZATION OF SODIUM BICARBONATE-CITRIC ACID CONCENTRATION IN APHRODISIAC EFFERVESCENT GRANULE DOSAGE FORM OF A COMBINATION OF JAVANESE CHILI EXTRACT AND RED GINGER EXTRACT AND EVALUATION OF ITS PHYSICAL PROPERTIES

RIZA MAULANA, ARIFAH SRI WAHYUNI, MUHAMMAD DAI

193-200
COMPARATIVE PHYSICOCHEMICAL EVALUATION OF DIFFERENT POLYMERS AS A MATRIX FOR THE FORMULATION OF SUSTAINED RELEASE TABLET USING FACTORIAL DESIGN

ALAA BUR, ABDULLAH H. MAAD, YUSRA AHMED, MALAZ YOUSEF, ZUHEIR OSMAN

201-209
BIOEQUIVALENCE STUDY OF A 400 MG INTRAVAGINAL PROGESTERONE PESSARY USING TANDEM MASS SPECTROMETRY IN FEMALE SUBJECTS

AHMAD ABU-AWWAD, BASIL ARAFAT, TAWFIQ ARAFATE

210-215
DEVELOPMENT AND VALIDATION OF AN RP-HPLC CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF RELATED SUBSTANCES IN A POLYPHARMACEUTICAL ORAL SUSPENSION WITH ION EXCHANGE RESIN-BASED TASTE MASKING

ROBINDRA K. PANDIT, VIVEK PANDEY

216-230
QUALITY BY DESIGN DRIVEN FORMULATION DEVELOPMENT AND OPTIMIZATION OF POOR SOLUBLE ANTI-HYPERTENSIVE DRUG FOR IMPROVED SOLUBILITY

DEEPTI AGGARWAL, RAM DAYAL GUPTA, VIJAY SHARMA

231-240
QBD (QUALITY BY DESIGN) APPROACH: DEVELOPMENT AND VALIDATION OF AN RP-HPLC METHOD FOR ESTIMATING IMEGLIMIN HCL AND ITS KETONE IMPURITY

POOJA T. GIRI, ANURUDDHA R. CHABUKSWAR, SWATI C. JAGDALE, SANTOSH A. CHINDHE

241-253
SCREENING AND CHARACTERIZATION OF FAVIPIRAVIR-LOADED NANOSTRUCTURED LIPID CARRIER FORMULATIONS BY USING A 26-2 FRACTIONAL FACTORIAL DESIGN

MAXIUS GUNAWAN, DAVID G. FERNIG, VEERAKIET BOONKANOKWONG

254-267
ABIRATERONE ACETATE LOADED SODIUM ALGINATE NANOPARTICLES FOR IMPROVING AQUEOUS SOLUBILITY AND DISSOLUTION OF ABIRATERONE ACETATE: PREPARATION AND FORMULATION OPTIMIZATION BY CENTRAL COMPOSITE DESIGN, CHARACTERIZATION

NALLAMUTHU M., UMADEVI S.

268-278
INVESTIGATING THE EFFICACY OF CURCUMIN NANOEMULGEL IN COMBATING BACTERIAL ACTIVITY USING AGAR DIFFUSION METHOD AND BROTH DILUTION METHOD

JOSHNA BOORAVILLI, JANAKI DEVI SIRISOLLA

279-289
POTENTIATION OF CIPROFLOXACIN ACTIVITY BY CHALCONES BY MODULATING EFFLUX PUMP AND BIOFILM REGULATORY GENE IN STAPHYLOCOCCUS AUREUS

BHAWANDEEP KAUR, SHASHIKANTA SAU, SUMAN K. JANA, NITIN PAL KALIA, GOPAL LAL KATHIK, ASHISH SUTTEE, SARIKA SHARMA, SANDEEP SHARMA

290-298
FORMULATION AND EVALUATION OF TOPICAL TRANSFEROSOMES LOADED LIDOCAINE FOR TOPICAL DELIVERY FOR BURNS, IN VITRO CHARACTERIZATION AND IN VIVO STUDY

SARMAD DHEYAA NOORI, SAMER KHALID ALI, MUSTAFA MUDHAFAR, HASAN ALI ALSAILAWI, AMIRA B. KASSEM

299-308
IN-SILICO MOLECULAR DOCKING STUDIES, SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF NEW PYRAZOLINE DERIVATIVES BEARING PYRIDINE RING SCAFFOLDS

MOHAMMED CHASIB MAWLA, TAGREED N-A OMAR

309-325
FORMULATION AND EVALUATION OF MOUTH-DISSOLVING ORAL FILM OF NICOTINE USING QUALITY BY DESIGN APPROACH

SACHIN DATTRAM PAWAR, NAGOJI SHINDE, GUNDAWAR RAVI, TUKARAM KALYANKAR

326-336
IN VIVO PHARMACOKINETICS STUDY OF DICLOFENAC SODIUM LOADED BASELLA ALBA MUCILAGE BASED CARRIER FOR ENHANCEMENT OF ORAL BIOAVAILABILITY

MOUMITA CHOWDHURY, PINTU KUMAR DE

337-343
QUERCETIN PHYTOSOMES: A COMPREHENSIVE APPROACH FOR THE PREPARATION AND OPTIMIZATION USING BOX-BEHNKEN DESIGN

SRIKALA KAMIREDDY, SHANMUGA SUNDARAM SANGEETHA, HAREKRISHNA ROY

344-357
QUALITY BY DESIGN ASSOCIATED IBRUTINIB LOADED NANOSUSPENSION FOR AMELIORATED DISSOLUTION USING NANO BALL MILLING AND SPRAY DRYING METHODS

VALLABH DEULKAR, RAGHUVEER PATHURI

358-369
DEVELOPMENT AND VALIDATION OF A GRADIENT PROGRAM RP-HPLC METHOD FOR ESTIMATION OF MULTIPLE ACTIVE PHARMACEUTICAL INGREDIENTS IN AN ORAL SUSPENSION TASTE MASKED WITH AN ION EXCHANGE RESIN

ROBINDRA K. PANDIT, VIVEK PANDEY

370-386
COMPUTATIONAL DRUG DESIGN AND MOLECULAR DYNAMICS OF PHENYL BENZAMIDE DERIVATIVES AS PARP-1 INHIBITORS FOR BREAST CANCER THERAPY

PULLA PRUDVI RAJ, DIVYA JYOTHI PALATI, PRAVEEN T. K., GOWRAMMA B.

387-394
NANOPARTICLE PREPARATION OF SNAKEHEAD FISH EXTRACT (CHANNA STRIATA) BY IONIC GELATION METHOD USING CHITOSAN AS POLYMER

MOHAMAD ANDRIE, WINTARI TAURINA

395-400
IN SILICO DESIGN AND IDENTIFICATION OF POTENTIAL D-ALA: D-ALA LIGASE INHIBITORS AGAINST STAPHYLOCOCCUS AUREUS

ABISHA THOMAS, MD. AFZAL AZAM

401-407
DESIGN OF EXPERIMENTS-BASED OPTIMIZATION OF ORAL THIN FILM FORMULATION OF ESCITALOPRAM OXALATE FOR ENHANCED PATIENT COMPLIANCE

SUMANTH BHUKYA, JAYAPAL REDDY GANGADI, POLI REDDY PAPAGATLA

408-419
A LIQUID CHROMATOGRAPHIC METHOD FOR THE RELIABLE QUANTIFICATION OF UPADACITINIB AND ITS SPECIFIED IMPURITIES

SUBHASHINI KANTHETI, RUDRARAJU RAMESH RAJU, GIRI PRASAD GORUMUTCHU

420-434
FORMULATION OF ANTI-DIABETIC ULCER GEL ENRICHED WITH ALOE VERA EXTRACT AND FISH COLLAGEN: AN IN VIVO STUDY

JULIA REVENY, SONY EKA NUGRAHA, ADIRA KAMILIA, NURATIKA

435-443
INVESTIGATION OF URINARY METABOLOMIC PROFILING FOLLOWING EXPOSURE TO ULTRAVIOLET RADIATION-A BY USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (LC-MS)

ALI MUHSEN ALI, AHMED M. ZHEOAT, HUSSEIN ALI KAREEM, MUSTAFA KAREEM HASSAN

444-452
A NOVEL TOPICAL GEL OF THE FRESH YOUNG COCONUT HUSK ETHANOLIC EXTRACT DEDICATED FOR DIABETIC WOUND HEALING

CHRISTOFORI MARIA RATNA RINI NASTITI, YOHANES DWIATMAKA, CHRISTINE PATRAMURTI, MICHAEL RAHARJA GANI, FLORENTINUS DIKA OCTA RISWANTO

453-461
DEVELOPMENT AND VALIDATION OF UV-SPECTROPHOTOMETRIC AND RP-HPLC METHODS FOR CURCUMIN-TOFACITINIB NANOCARRIERS: A NOVEL PLATFORM FOR ENHANCED BREAST CANCER THERAPY

SUCHITA WAGHMARE, UJBAN MD HUSSAIN, NILESH RAROKAR, PRAMOD KHEDEKAR

462-470
AN INVESTIGATION ON CERVICAL CANCER DRUGS THROUGH QSPR MODEL EMPLOYING DEGREE-RELATED TOPOLOGICAL INDICES

PRIYADARSHINI S., S. KOPPERUNDEVI

471-482
ARTIFICIAL INTELLIGENCE POWERED DESIGN OF EXPERIMENTS: OPTIMIZING ABIRATERONE ACETATE LOADED GELATIN NANOPARTICLES FOR ENHANCED ORAL BIOAVAILABILITY OF ABIRATERONE ACETATE

NALLAMUTHU M., UMADEVI S., ANANDAN R.

483-496
REPURPOSED SIMVASTATIN-LOADED NANOSTRUCTURED LIPID CARRIERS: OPTIMIZATION, CHARACTERIZATION AND EVALUATION AGAINST LUNG CANCER

NARGIS ARA, ABDUL HAFEEZ, SHOM PRAKASH KUSHWAHA, ARCHITA KAPOOR

497-510
HPTLC QUANTIFICATION OF 4, 4’-METHYLENE BIS (2,6-DI-TERT-BUTYL PHENOL) IN FLAX MICROGREEN EXTRACTS AND ITS ANTICANCER POTENTIAL AGAINST PROSTATE CANCER

MUDASSIR LAWAL, NEETA RAJ SHARMA, AWADHESH KUMAR VERMA, IBRAHIM HAMZA KANKIA, VETRISELVAN SUBRAMANIYAN, GURMEEN RAKHRA

511-520
FORMULATION AND EVALUATION OF NANO FORMULATION OF BTK INHIBITOR BY BOX-BEHNKEN DESIGN AND HIGH-PRESSURE HOMOGENIZATION FOR ENHANCED BIOAVAILABILITY AND REDUCING THE EFFECTS OF FOOD

S. SREENIVASA CHARY, D. V. R. N. BHIKSHAPATHI, V. V. RAJESHAM, SAILAJA RAO PENAKALAPATI, PAMU SANDHYA, RUBESH KUMAR SADASIVAM

521-528
EVALUATION OF ORGAHEALTM TURMERIC CURCUMIN WITH BOSWELLIA, GINGER AND BLACK PEPPER CAPLET ROLE IN MODULATING INFLAMMATION AND JOINT FUNCTION

RAJENDRAN A., R. SUDESH RAJ, TEJAS M., S. JAYAKUMAR, S. REETHI, S. SNEHA

529-540
INNOVATIVE UPLC METHOD FOR CONCURRENT QUANTIFICATION AND PHARMACOKINETIC ANALYSIS OF NIRMATRELVIR AND RITONAVIR IN RAT PLASMA

GOPE EDWARD RAJU, SRIKANTH POTTENDLA, SUNEETHA YAPARTHI

541-548
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