DEMOGRAPHIC PROFILE AND CLINICAL OUTCOMES OF ALUMINUM PHOSPHIDE POISONING: A PROSPECTIVE STUDY
DOI:
https://doi.org/10.22159/ijcpr.2025v17i6.8013Keywords:
Aluminum phosphide poisoning, Demographic profile, Phosphine toxicityAbstract
Objective: To analyze the demographic distribution, clinical presentation, and outcomes of ALP poisoning cases admitted to a tertiary care hospital in Bhopal, Madhya Pradesh.
Methods: A prospective observational study was conducted on 44 patients diagnosed with ALP poisoning over a one-year period. Data were collected on age, gender, domicile, clinical symptoms, and outcomes.
Results: The majority of cases occurred in the 21–30 age group (56.82%), with males (56.82%) slightly more affected than females (43.18%). Rural and urban populations were equally affected (50% each). Common symptoms included nausea (38.64%), vomiting (34.09%), and diarrhea (22.73%). Mortality was high, with (72.73%) of patients succumbing to the poisoning.
Conclusion: ALP poisoning continues to be a serious public health issue in both rural and urban India. The high fatality rate underscores the need for tighter control on its sale and improved clinical management strategies.
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1. Chugh SN, Dushyant, Ram S, Arora B, Malhotra KC. Incidence & outcome of aluminium phosphide poisoning in a hospital study. Indian J Med Res. 1991;94:232-5. PMID 1937606.
2. Proudfoot AT. Aluminium and zinc phosphide poisoning. Clin Toxicol (Phila). 2009;47(2):89-100. doi: 10.1080/15563650802520675, PMID 19280425.
3. Mehrpour O, Singh S. Rice tablet poisoning: a major concern in Iranian population. Hum Exp Toxicol. 2010;29(8):701-2. doi: 10.1177/0960327109359643, PMID 20097728.
4. Shadnia S, Soltaninejad K, Hassanian Moghaddam H. Metabolic acidosis in aluminum phosphide poisoning. Hum ExpToxicol. 2009;28(11):665-8.
5. Bumbrah GS, Krishan K, Kanchan T, Sharma M, Sodhi GS. Phosphide poisoning: a review of literature. Forensic Sci Int. 2012;214(1-3):1-6. doi: 10.1016/j.forsciint.2011.06.018, PMID 21763089.
6. Gupta S, Ahlawat SK. Aluminum phosphide poisoning a review. J Toxicol Clin Toxicol. 1995;33(1):19-24. doi: 10.3109/15563659509020211, PMID 7837309.
7. Mathai A, Bhanu MS. Acute aluminium phosphide poisoning: can we predict mortality. Indian J Anaesth. 2010;54(4):302-7. doi: 10.4103/0019-5049.68372, PMID 20882171.
8. Hassanian Moghaddam H, Shahnazi M, Zamani N. Aluminium phosphide poisoning: an evidence-based review of current management. Indian J Crit Care Med. 2016;20(10):588-95. doi: 10.4103/0972-5229.195712.
9. Mehrpour O, Singh S. Rice tablet poisoning: a major concern in Iranian population. Hum Exp Toxicol. 2010;29(8):701-2. doi: 10.1177/0960327109359643, PMID 20097728.
10. Wahab A, Zaheer MS, Wahab S, Khan RA. Acute aluminium phosphide poisoning: an update. HK J Emerg Med. 2008;15(3):152-5. doi: 10.1177/102490790801500306.
11. Bumbrah GS, Krishan K, Kanchan T, Sharma M, Sodhi GS. Phosphide poisoning: a review of literature. Forensic Sci Int. 2012;214(1-3):1-6. doi: 10.1016/j.forsciint.2011.06.018, PMID 21763089.
12. Hassanian Moghaddam H, Shahnazi M, Zamani N. Aluminium phosphide poisoning: an evidence-based review of current management. Indian J Crit Care Med. 2016;20(10):588-95. doi: 10.4103/0972-5229.195712.
13. RH, Mg R, KN S. Acute aluminium phosphide poisoning: an under-reported Problem in India. JCBS. 2021;11(4):140-2. doi: 10.58739/jcbs/v11i4.1.
14. Saroj S, Singh P, Kulshrestha V, Bhatnagar S. Pattern of aluminum phosphide poisoning at a Tertiary Care Hospital in Saifai, Etawah. J Forensic Med Toxicol. 2024;41(1):9.
15. Sarkar MK, Ghosh N, Rakesh U, Prasad R, Raj R. Acute aluminium phosphide poisoning: a case report of rare survival with cardiac metabolic, hepatic and renal complications. J Fam Med Prim Care. 2022;11(11):7452-5. doi: 10.4103/jfmpc.jfmpc_615_22, PMID 36993112.
16. Hassanian Moghaddam H, Shahnazi M, Zamani N. Aluminium phosphide poisoning: an evidence-based review of current management. Indian J Crit Care Med. 2016;20(10):588-95. doi: 10.48165/jfmt.2024.41.1.9.
17. Gurjar M, Baronia AK, Azim A, Sharma K. Managing aluminum phosphide poisonings. J Emerg Trauma Shock. 2011;4(3):378-84. doi: 10.4103/0974-2700.83868, PMID 21887030.
18. More DB, Malve H, Wankhede MN. Multidisciplinary approach to aluminium phosphide poisoning. Toxicol Int. 2021;28(4):403-9. doi: 10.18311/ti/2021/v28i4/28095.
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