THE EFFECT OF ORIGANUM VULGARE GEL ADDITION TO AUTO-POLYMERIZED SILICONE SOFT DENTURE LINER AT VARYING CONCENTRATIONS AND EXPOSURE TIMES ON SURFACE ROUGHNESS AND ANTIFUNGAL ACTIVITY AGAINST CANDIDA ALBICANS

ARIYANI; CRYSTHEVANY DAMERIA GIRSANG; FARAH NAURAH SALSABILA NASUTION

doi:10.22159/ijap.2025.v17s5.15

Authors

ARIYANI Department of Prosthodontics, Faculty of Dentistry, Universitas Sumatera Utara, Medan, Indonesia
CRYSTHEVANY DAMERIA GIRSANG Faculty of Dentistry, Universitas Sumatera Utara, Medan, Indonesia
FARAH NAURAH SALSABILA NASUTION Faculty of Dentistry, Universitas Sumatera Utara, Medan, Indonesia

DOI:

https://doi.org/10.22159/ijap.2025.v17s5.15

Keywords:

Origanum vulgare, Oregano gel, Auto-polymerized silicone soft denture liner, Silicone soft liner, Surface roughness

Abstract

Objective: Soft denture liners (SDLs) present certain drawbacks, such as weak bonding with the acrylic resin denture base and increased surface roughness, which may result in porosity. These factors can compromise SDL and the denture base, thereby promoting the colonization of Candida albicans.

Methods: A total of 120 samples were divided into four concentration groups (0%, 6.25%, 12.5%, and 25%) and three exposure time groups (7, 14, and 21 days). Each group was tested for antifungal inhibition activity and surface roughness using a universal testing machine. Data were analyzed using one-way ANOVA with Dunnett’s T3 post-hoc test to determine the significance of differences among groups (p<0.05).

Results: The addition of oregano gel significantly affected the surface roughness between the SDL and the denture base. Higher concentrations and longer exposure times compromised SDL-denture base adhesion, promoting Candida albicans colonization. Among the treatment groups, 6.25% oregano gel demonstrated better performance compared to nystatin, maintaining higher bond strength and reducing fungal adhesion.

Conclusion: The addition of 6.25% oregano gel improved the antifungal effect while maintaining adequate surface roughness of the SDL to the denture base, outperforming nystatin under similar conditions.

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