EVALUATION OF SKELETAL MUSCLE RELAXANT ACTIVITY OF CYMBOPOGON CITRATUS IN MICE
DOI:
https://doi.org/10.22159/ijcpr.2025v17i4.7000Keywords:
Cymbopogon citratus, skeletal muscle relaxant, Rota rod apparatus (RRA) and Inclined plane model (IPM).Abstract
Objective: To evaluate skeletal muscle relaxant of Ethanolic extracts of Cymbopogon citratus leaves in albino mice by using Rota rod method and Inclined plane model.
Methods: Healthy, adult Swiss albino mice of either sex weighing (25-40 g), maintained under standard laboratory conditions, at temperature 25±2 °C and a 12 h light-12 h dark period employed for the experimentation. Food and water provided ad libitum.
Results: In the present study, the skeletal muscle relaxant activity of ethanolic extract of Cymbopogon citratus in Swiss albino mice at the dose of 250 and 500 mg/kg with oral administration respectively.
Conclusion: In conclusion, both the doses of 250 and 500 mg/kg with oral administration have shown significant results as skeletal muscle relaxant effect using rota rod method and Inclined plane model.
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Copyright (c) 2025 APOORAV MISHRA, AJEET PAL SINGH, AMAR PAL SINGH
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